Biofilms in Medical Contexts

System

Impact of Biofilm Formation

References
General Persistent infections Costerton et al., Science 284:1318-1322 (1999)

Potera, Science 283:1837 (1999)

J. California Dental Association 29(5):347-369 (2001)

Costerton and Stewart, Scientific Amer 285(1):74-81 (2001)

Hall-Stoodley et al, Nature Reviews Microbiology, 2(2):95-108 (2004)
 
Dental plaque Caries, gingivitis, periodontitis Marsh and Bradshaw, J. Ind. Microbiol 15:169 (1995)

Darveau et al, Periodontol 2000 14:12 (1997)

Page et al, Periodontol 2000 14:216
Chronic infections

  - Otitis media
  - Cystic fibrosis
     pneumonia
  - Biliary tract
     infections
  - Osteomyelitis
  - Bacterial
     prostatitis
  - Native heart
     valve
  - Urinary tract
  - Diabetic foot ulcers
  - Decubitis ulcers
  - Venous leg ulcers
  - Sinusitis (?)
  - Tonsilitis (?)
  		Persistent infection Fux et al, TRENDS in Microbiology 13(1):34-40 (2005)

Donlan, Emerging Infect Dis., 7(2):277-281 (2001)

Ehrlich, et al, ASM News, 70(3):127-133 (2004)

Percival and Bowler, Wounds 16(7):234-239 (2004)
Catheters

  - Urinary
  - Vascular
  - Central venous
  - Hickman
  - Swan-Ganz
  - Periotoneal dialysis
     (Tenckhoff)

 Contamination, drain blockage, endocarditis Fux et al, Expert Rev. Anti-infect. Ther., 1(4):89-105 (2003).
Implanted devices

  - Contact lenses
  - Biliary stents
  - Orthopedic devices
  - Prosthetic heart
     valves
  - Cardiac
     pacemakers
  - IUDs
  - Endotrachial tubes
  - Nasogastric tubes
  - Hemodialysis units

 Contamination,
infection